About Our Research
Research Road Map
CurePSP recognizes that the fight against PSP and other disorders can now take a new direction, capitalizing on a number of recent discoveries, exciting ongoing work and new hypotheses. To this end, CurePSP created the Research Road Map to help guide the organization's future scientific endeavors toward treatment and a cure. The Road Map will focus on three ideas in which PSP and other diseases may occur - genes, prions, and proteins. It will also focus on obtaining two tools used to explore those ideas - new models and new genetic markers. When combined, the Road Map hopes to accomplish five goals - identify new drug targets, screen potential drugs, develop tests using animal models, and implement both small and large scale testing in human patients.
The CurePSP Grants Program is divided into two areas of focus - traditional investigator-initiated grants and special initiative grants (SIG). With investigator-initiated grants, the scientific idea behind each grant is generated by the grantee, without any previous input from CurePSP, and the program allows even the most junior researchers to be eligible. The SIG program was created to facilitate and support grants that would require major funding and are typically reserved for well-established and accomplished researchers.
Collaboration with the Tau Consortium
CurePSP is working with the Tau Consortium, a group of 15 investigators supported by the Rainwater Charitable Foundation, toward a similar goal - to find causes and treatments for PSP. Currently, CurePSP and the Tau Consortium are collaborating on a project to investigate the relationship between PSP and a rare tau disorder called "lytico-bodig", which occurs only on Guam and nearby islands. Fortunately yet mysteriously, Lytico-bodig is dying out. CurePSP hopes that if the reasons for its dissipation can be identified, perhaps it may open a similar path forward with PSP.