Currently Funded Venture Grants
CurePSP provides seed funding to investigators who have innovative ideas and that need to establish or confirm proof of concepts in order to qualify for larger funding sources. Please find below a list of currently funded researchers.
Newly Funded 2021
Dr. Marta Olah, Department of Neurology, Columbia University, New York, NY
Identification of Microglia Phenotypes Associated with Tau Pathology in PSP and CBD
Dr. Maria Catarina Lima da Silva, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Investigation of ULK1-Based Autophagy Activators as Therapeutics for Tauopathies
Dr. Daniel H. Geschwind, Department of Neurology, UCLA, Los Angeles, CA
Aminopeptidase Enhancers as Novel PSP Pharmacotherapies
Dr. Rachel Baily, Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern Medical Center, Dallas, TX
Gene Replacement Therapy for Tauopathies
Ongoing Funded Grants
Dr. Franziska Hopfner, Department of Neurology, Hannover Medical School, Hannover, Germany
MicroRNA profile of isolated brain cell populations in PSP
Dr. Chao Peng, Department of Neurology, UCLA David Geffen School of Medicine, Los Angeles, California
The Role of Post-Translational Modifications on Tau Transmission in PSP
Dr. Rohan de Silva, UCL Queen Square Institute of Neurology, London, UK
Do distinct 4R-tau seeding strains cause disease heterogeneity in PSP and CBD?
Dr. Rik van der Kant, Functional Genomics Department, Vrije Universiteit Amsterdam, Amsterdam, Holland
Low-dose efavirenz as a disease-modifying intervention for primary Tauopathies
Dr. Rueben Das, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
Connecting GWAS signal in TAU Locus to Effector Variant in Tauopathies
Dr. Geidy E. Serrano, Banner Sun Health Research Institute, Sun City, AZ
Single-Whole-Cell Characterization in Progressive Supranuclear Palsy
Dr. Amanda L. Woerman, University of Massachusetts, Amherst, MA
Investigating PSP and CBD Tau Strain Biology to Support Novel Diagnostic Development
Dr. John M. Ringman, Keck School of Medicine at the University of Southern California, Los Angeles, CA
Genotyping Familial Progressive Supranuclear Palsy
Dr. Lukasz Joachimiak, Center for Alzheimer’s and Neurodegenerative Diseases, UT Southwestern Medical Center, Dallas, TX
Structural Basis for Tau Strain Conformation in CBD and PSP
Dr. Kenneth Matthew Scaglione, Molecular Genetics and Microbiology, Duke University, Durham, NC
Small Molecule Regulation of a Protein Quality Control E3 to Treat PSP
Dr. Mark Cooper, Institute of Neurology, Dept of Clinical and Movement Neurosciences, University College London, London, England
The Influence of TRIM11on Tau, Aggregation, Release and Propagation
Dr. David C. Butler, Neural Stem Cell Institute, Regenerative Research Foundation, Rensselaer, NY
Bifunctional Intrabodies to Lower Tau
Dr. Gal Bitan, University of California, Los Angeles
Biomarkers In Brain-Derived Blood Exosomes For Improved PSP Diagnosis
Dr. Todd J. Cohen, The University of North Carolina at Chapel Hill, NC
Uncovering Unique Tau Profiles That Distinguish PSP From Other Tauopathies
Dr. Maria-Elena Avale, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Buenos Aires, Argentina
Dissecting Neuronal Dysfunctions Under 3R:4R Tau Isoforms Imbalance