Understanding the Diseases

PSP, CBD and MSA are progressive, neurological diseases caused by abnormal folding of proteins in brain cells. There are no cures yet, but treatments and support are available.

Progressive Supranuclear Palsy
Corticobasal Degeneration
Multiple System Atrophy


Progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and multiple system atrophy (MSA) are brain diseases that can cause changes to speech, balance, walking, swallowing, vision, cognition and autonomic functioning. They can also involve symptoms similar to Parkinson’s disease including tremor, stiffness and slowness. Because of this, people may initially be diagnosed with Parkinson’s and you may hear PSP, CBD and MSA referred to as “atypical parkinsonism” syndromes. They are neurodegenerative, meaning that symptoms may change and worsen over time.

PSP, CBD and MSA are considered rare, especially compared to more common neurodegenerative diseases of Alzheimer’s disease and Parkinson’s disease. However, about 25% of people with PSP, CBD and MSA are accurately diagnosed. Many healthcare providers are not familiar with these conditions, leading to an often lengthy and complex diagnosis journey. At this time, treatment cannot slow the progression of these diseases, although there are many options to manage symptoms and care. Educating the medical community to lead to accurate diagnosis and improved care is a priority of CurePSP.

We recognize that a diagnosis of PSP, CBD or MSA can bring about many questions, emotions and complex care considerations. We are here to provide education and to support you through your journey.

Educational Resources

CurePSP maintains a library of educational resources, which you can download or order, to offer guidance and tools for life with PSP, CBD or MSA.

See Our Full Catalogue Of Available Resources

Newly Diagnosed Checklist

We have created a comprehensive checklist to aid you in navigating a recent diagnosis of PSP, CBD or MSA. Use this helpful guide to easily connect with the CurePSP community, learn how to become your own advocate and stay proactive along your journey.

View Our Newly Diagnosed Checklist


CurePSP has a comprehensive plan and supports research that may ultimately find treatments and cures for PSP, CBD, MSA and related neurodegenerative diseases.

Learn More About Research


CurePSP offers Ask the Expert webinars, Family Conferences, Wellness Wednesdays and more as opportunities for education on PSP, CBD and MSA.

See Our Full Collection Of Archived Videos

Resources for Healthcare Professionals

CurePSP strives to provide healthcare professionals with information and resources to help in diagnosing, treating, and managing PSP, CBD and MSA.

Learn More Here

CurePSP Newsletter

The bi-annual CurePSP Connection newsletter helps keep our community updated on the latest stories and news from the foundation.

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