What is CBD?

Corticobasal degeneration (CBD) is a neurodegenerative brain disease that has no known cause, treatment or cure. It affects nerve cells that control walking, balance, mobility, vision, speech, and swallowing.

CBD is rare, affecting an estimated 2000-3000 people in United States, of whom only 500-750 are diagnosed.

Symptoms begin, on average, when an individual is in the early 60's, but may start as early as in the 40's. These include:

  • Stiffness, shakiness, jerkiness, slowness, and clumsiness in either the upper or lower extremities

  • Difficulty with speech generation (dysphasia)

  • Difficulty with articulation (aphasia)

  • Difficulty controlling the muscles of the face and mouth (dysarthria)

  • Walking and balance difficulty

  • Asymmetric onset of symptoms (occuring on one side of the body first then gradually moving to the other side)

  • Memory or behavior problems

Below is a large collection of in-depth information on the disease including its background, symptoms and treatment options, among other things.

Articles, Documents and Publications