February 12, 2014

CurePSP Awards $1.2 Million for New Research Grants

CurePSP is pleased to announce its latest round of funding for researchers who are working toward unlocking the mysteries of PSP, CBD, MSA and other atypical Parkinsonian disorders. The Foundation's Board of Directors has approved the allocation of more than $1.2 million in funds to support the following research grants:

Development and Validation of the Unified CBD Rating Scale
Irene Litvan, MD
University of California, San Diego
San Diego, California
Lawrence I. Golbe, MD
Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey

Whole-Exome Sequencing Project
Gerard Schellenberg, PhD
University of Pennsylvania
Philadelphia, Pennsylvania

Impact of Arginase1 Over-Expression and SAT1 Deficiency During Tauopathies
Daniel C. Lee, PhD
University of South Florida
Tampa, Florida

The Role of O-linked Protein Glycosylation in the Spread of Tau Pathology
Christoph Wiessner, PhD
Asceneuron SA
Lausanne, Switzerland

Disease Modifying Tau Immune Therapy for PSP and CBD
John Trojanowski, MD, PhD and Virginia M.-Y. Lee, PhD
University of Pennsylvania
Philadelphia, Pennsylvania

Epigenetic Modifications in PSP (extension)
Ulrich Müller, MD, PhD
Justus Liebig University Giessen
Giessen, Germany
Günter U. Höglinger, MD
German Center for Neurodegenerative Diseases & Technical University Munich
Munich, Germany

These new research grants are part of CurePSP's $15 million Research Road Map initiative. The Research Road Map aims to accomplish five goals - identification of new drug targets, screening of potential drugs, development of tests using animal models, and implementation of both small-scale human testing and large-scale testing in patients. These projects may also have implications for other brain diseases caused by protein tangles, such as Alzheimer’s disease, Parkinson’s disease, Lou Gehrig’s disease (ALS), fronto-temporal dementia (FTD), and chronic traumatic encephalopathy (CTE) as a result of athletic trauma or military injury.

CurePSP is the foremost non-profit organization dedicated to increasing awareness of progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), and other atypical Parkinsonian disorders; funding research toward treatment, cure and prevention; educating healthcare professionals; and providing support, information and hope for affected persons and their families.