Clinical trials help researchers answer important medical questions, providing information that may help with the development of future treatment options. Clinical trials are conducted to determine if investigational treatments (such as new drugs, procedures, or medical devices) are safe and effective, so that the regulatory authority can decide whether they can be approved for use as a treatment.
Participation in a clinical trial is voluntary. You can withdraw at any time, for any reason (or no reason at all), and doing so will not affect the care you may be receiving now and may receive in the future.
Disclaimer: the videos and the brochure were produced by Biogen, a pharmaceutical company with whom we collaborate. This material does not intend to favor one or the other clinical trial, and CurePSP remains fully impartial in its support of clinical research.
Current Clinical Trials
For a current list of available clinical trials (sourced from the National Institutes of Health website, clinicaltrials.gov), please click on the following links:
Opportunity to participate in a research trial! The University of Florida is looking for individuals with progressive supranuclear palsy (PSP), multiple system atrophy parkinsonian type (MSA-P) or Parkinson’s disease to participate in a study testing the performance of automated imaging differentiation of parkinsonism (AIDP) software in recognizing the different diagnoses. The study is being offered at over 20 locations across the U.S. and Canada.
The ORION Trial
A phase 3 Clinical Trial for People Living with Progressive Supranuclear Palsy (PSP).
The ORION Study is looking at a potential new medication, also called an “investigational drug”, for a condition called progressive supranuclear palsy, or “PSP”.
The ORION Study is looking to see whether the investigational drug:
- has an effect on the progression of PSP
- has good safety and tolerability (which means the body handles taking it well). About 600 people from different countries across the world are expected to take part in this study.
The study will have two parts, which are also called “treatment periods”. Each treatment period will last around a year.
Treatment of Disturbed Sleep in PSP
UCSF is recruiting for a study to explore if specific sleep medications can improve your sleep patterns, disease symptoms, or quality of life. This is a 6-week remote clinical sleep trial in PSP, meaning you can fully participate from your own home with frequent phone calls with the study team.
The 4 Repeat Tauopathy Neuroimaging Initiative. The goal of this study is to identify the most reliable methods of analysis for tracking CBD and PSP over time. The results from this study may be used in the future to calculate statistical power for clinical drug trials. The study will also provide information about the relative value of novel imaging techniques for diagnosis, as well as the value of imaging techniques versus testing of blood, urine, and cerebrospinal fluid (CSF) ‟biomarkers.”
The FTD Disorders Registry
The Registry is an online database to collect information from those affected by all types of prime of life brain diseases, such as PSP, CBD, and related. Persons diagnosed, (current/former) caregivers, family, and friends can join. As a member of the Registry, you can help us advance the science and move faster toward finding treatments and cures. Join the registry here.